Scientist, Molecular Biology @Brink Therapeutics

Scientist, Molecular Biology @Brink Therapeutics Join us We usually respond within two weeks Brink Therapeutics is a venture-backed biotech company specializing in the development of cutting-edge gene therapy tools. We focus on site-specific recombinases, highly efficient enzymes that enable precise DNA modifications - such as inserting, removing, or inverting DNA sequences - without causing double-strand breaks. These recombinases offer a safer, more precise alternative to existing technologies like CRISPR-Cas9, giving them the potential to revolutionize Cell and Gene Therapies and finally push them over the brink of mass accessibility. By joining Brink Therapeutics, you will become part of a passionate and growing team at an exciting inflection point - with meaningful progress behind us and significant momentum ahead as we advance toward our Series A. Together, we are building an ambitious company harnessing advanced Directed Evolution, deep gene-mining techniques and AI to unlock new possibilities for treating & curing cancers, genetic disorders and beyond. If you are an innovative scientist or engineer excited about working together to solve hard, longstanding problems to improve patients’ lives around the world, we are looking for passionate individuals to join our team and help shape the future of medicine! Mission Highlights As a Scientist, Molecular Biology , you will be responsible for helping expand and execute our advanced in vitro droplet-based recombinase Directed Evolution platform, with the ultimate goals of generating and characterizing in vitro lead recombinase enzyme candidates of high therapeutic utility and generating massive NGS datasets for computational colleagues to extract learnings from. Responsibilities Develop & execute processes for the design and generation of ultra-large, smart recombinase variant libraries (in collaboration with computational scientists) Develop & execute in vitro droplet-based recombinase Directed Evolution assays starting from our existing platform (microfluidics expertise not required) Develop & execute NGS-based processes for efficient readout of Directed Evolution assays Develop & execute in vitro assays for the rapid characterization of key recombinase functional and biochemical properties Communicate project status, requirements, risks and mitigation to stakeholders Perform critical data analysis (with computational scientist support as needed), maintain detailed electronic laboratory records, present results to stakeholders Disclose research innovations to internal stakeholders to secure IP protection Competencies You feel at home in the wet lab, designing experiments and generating & interpreting data. You enjoy communicating your findings in a clear and actionable manner, particularly to fellow scientists in both the wet and dry lab. You are conscious of maximizing the value of your research activities by employing good documentation practices. You are a sharp and collaborative trouble-shooter who doesn’t shy away from the hard problems. Required: MSc with 2+ years of experience or PhD in molecular biology, biochemistry or related fields, and eagerness to keep learning Proven record of innovative problem-solving skills Demonstrated expertise in experimental design, assay development and data analysis Excellent written and oral communication English - professional working proficiency Motivation to work in a flexible and fast-paced startup The ideal candidate will also have some of the following: Experience working in fast-paced startup environments Expertise in Directed Evolution, gene library synthesis, and NGS Expertise in recombinase enzymology Recruitment Process We first check that your profile meets our requirements An introductory call with one of the founders Technical and value-fit interviews with wider team, on-site Why join us? Unique opportunity to be part of an early-stage biotech company, shaping the future of genome editing for Cell and Gene Therapy Competitive salary + benefits package Beautiful, well-equipped offices & labs in the heart of Paris, filled with great plants and great people If you're excited about helping revolutionize genome editing and opening up Cell & Gene Therapy to the millions who could benefit, apply now, and let's make the difference together! Department Join our startups Role Tech Locations Paris Remote status Hybrid Employment type Full-time