At GeneDx (Nasdaq: WGS), we don’t just diagnose rare diseases — we redefine what’s possible in precision medicine. With one of the world’s largest, rare disease datasets, we turn genomic data into answers that change lives and accelerate discovery. Patients and families around the world are counting on us to lead with bold ideas, relentless focus, and drive to end the diagnostic odyssey. Visit
www.genedx.com
to learn how we’re making precision medicine the global standard of care.
Summary
The Associate Clinical Analyst II (ABMGG-eligible or active candidate) supports the interpretation of genetic findings and contributes to accurate diagnosis and case resolution through exome and genome sequencing. This entry-level role focuses on building foundational clinical analysis skills by assisting with case reviews under supervision, performing routine data interpretation tasks. Responsibilities include supporting variant classification activities, preparing accurate documentation, and contributing to internal database updates. The Associate Clinical Analyst II ensures timely documentation, maintains quality standards, and aids departmental initiatives through collaborative engagement and continuous learning.
Shift:
Tuesday-Saturday or Sunday-Thursday 9am-5pm ET
How to Apply:
Please submit your resume
along with a cover letter
(required for consideration) detailing your experience and motivation for applying. Applications without a cover letter will not be considered.
Job Responsibilities
Perform clinical data analysis and case management to accurately interpret genetic findings.
Establish phenotype-genotype correlations across diverse genetic disorders.
Investigate and interpret clinical features of genetic conditions using internal resources and professional tools.
Review and finalize genetic test reports, interpret variants, and curate internal databases.
Serve as a subject matter expert for designated genes, disorders, tests, and workflows.
Communicate with clients via email, phone, or other channels to support case resolution and provider engagement.
May abstract clinical information from patient records.
Performs literature reviews and database searches to support variant interpretation and classification.
Meets or exceeds productivity and error standards as assigned by team lead.
Documents evidence and rationale for variant classification in a clear, standardized format.
Assist with development of variant-, gene-, or disease-specific test information and report language.
Perform other duties as assigned to support the team or department.
Credential-specific responsibilities include but are not limited to:
ABMGG Certified:
Fulfill responsibilities of
Clinical Consultant
as defined by CLIA (42 CFR 493.1457), including:
Consultation Availability: Provides timely consultation to ordering providers regarding test selection, interpretation, and clinical correlation of laboratory results.
Report Oversight: Reviews and ensures laboratory reports meet CLIA and CAP requirements for accuracy, completeness, and clinical relevance.
Result Authorization: Approves and signs off on high-complexity test results in accordance with CLIA regulations.
Education, Experience, and Skills
PhD in Biology, Genetics or related field, MD or DO with more than 2 years directly relevant experience in clinical diagnostics (including fellowship)
Excellent verbal and written communication skills
Demonstrated computer skills, including ability to maintain high proficiency with internal systems and Microsoft Office Suite and the Office 365 environment
Prior experience with variant curation is preferred but not required
Certificates, Licenses, Registrations
ABMGG certification or equivalent, certified in at least one specialty OR board eligible
Physical Demands
Prolonged periods of sitting or working at a computer in a home office environment
Occasional need to lift or move materials or equipment weighing up to 20 pounds during travel or team visits
Work Environment
Frequent use of digital communication platforms (e.g. video conferencing, email, and collaboration tools).
Ability to focus and manage complex tasks in a remote setting with multiple concurrent priorities.
May require occasional travel to laboratory sites, corporate offices, or conferences (typically <10%).
#LI-REMOTE
Pay Transparency, Budgeted Range
$150,000
—
$165,000 USD
~
Science - Minded, Patient - Focused.
At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.
Experts in what matters most.
With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.
SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.
From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:
TECHNICAL EXPERTISE
High-quality testing
: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
Advanced detection
: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.
CLINICAL EXPERTISE
Thorough analysis
: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
Customized care
: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
Impactful discovery
: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.
Learn more About Us
here
.
A culture that plays to win, because patients are counting on us
At GeneDx, we're driven by urgency and purpose: helping patients get diagnosed earlier. Our mission, to empower everyone to live their healthiest life through genomics, drives our team to make a tangible impact each day – and shapes our culture where high standards, strong teamwork, and meaningful ownership are the norm. We act with intention, support one another, and deliver work we're proud to put our names on.
Here’s what you can expect day to day:
1. Play like a champion (step up, redefine what’s possible, own it)
We bring energy, focus, and a bias for action. We step up, take initiative, and deliver on our commitments – with quality, speed, and care.
2. Think bigger (stretch beyond, courage not consensus)
We push past the obvious. We challenge assumptions, raise the bar, and make thoughtful, decisive calls — choosing progress over perfection.
3. Grow fast (be curious, speak up, be agile)
We stay curious, ask questions, and share direct feedback with respect. We adapt quickly and keep learning through collaboration and continuous improvement.
If you’re motivated by meaningful work, a fast-moving environment, and teammates who care deeply about outcomes, you’ll thrive at GeneDx.
Benefits include:
Paid Time Off (PTO)
Health, Dental, Vision and Life insurance
401k Retirement Savings Plan
Employee Stock Purchase Plan
Employee Discounts
Voluntary benefits
Programs for parents and parents-to-be
We provide expert support for family planning, pregnancy, and postpartum care, including up to 22 weeks of fully paid parental leave (U.S.) and up to $25K annually for fertility, adoption, or surrogacy.
GeneDx is an Equal Opportunity Employer.
All privacy policy information can be found
here
.